Insights into Enchondroma, Enchondromatosis and the risk of secondary Chondrosarcoma. Review of the literature with an emphasis on the clinical behaviour, radiology, malignant transformation and the follow up Minireview
نویسندگان
چکیده
1Department of Orthopaedics and Traumatology / Comprehensive Cancer Centre Freiburg, University Medical Centre Freiburg, Freiburg i. Br., Germany; 2Department of Orthopaedics and Traumatology, University Medical Centre Freiburg, Freiburg i. Br., Germany; 3Clinic for Radiology and Nuclear Medicine, Department for Nuclear Medicine , University Hospitaol Basle, Basle, Switzerland; 4Children’s Hospital , Division of Pediatric Hematology and Oncology, University Medical Centre Freiburg, Freiburg, Germany; 5Department of Radiology, University Medical Centre Freiburg, Freiburg i. Br, Germany; 6Institute of Pathology, University Medical Centre Aachen, Aachen, Germany; 7Department of Orthopaedics and Traumatology, University Medical Centre Freiburg, Freiburg i. Br., Germany; 8Department of Radiology , St. Josefshospital Freiburg, Freiburg i. Br., Germany
منابع مشابه
Chondrosarcoma of the nasal cavity in a patient with Maffucci syndrome: case report and review of the literature
INTRODUCTION Maffucci syndrome is a rare, congenital, non-hereditary mesodermal dysplasia, manifested by multiple enchondromas and hemangiomas. Malignant transformation of these lesions is seen in up to 40% of the cases. CASE REPORT We present a case of a patient with Maffucci syndrome and an associated chondrosarcoma of the nose. Treatment consisted of surgical resection. Because of the low ...
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In contrast to solitary enchondroma,patients with multiple enchondromatosis of bone (Ollier's disease) get affected in childhood by bone swelling and growth retardation. In adults, the main problem is the risk of malign transformation up to 40%.Pain, increasing local tumor and thinning of the corticalis are the typical clinical and radiological signs of transformation to a low grade chondrosarc...
متن کاملEnchondroma of the nasal septum due to Ollier disease: a case report and review of the literature.
BACKGROUND Morbus Ollier is characterized by the presence of multiple enchondromas (ie, benign intraosseous cartilaginous lesions). Although their manifestation in the limb bones is well described, only a few cases with ear, nose, and throat (ENT) involvement, primarily arising from the skull, have been reported. The malignant transformation toward slowly growing low-grade chondrosarcomas is th...
متن کاملEnchondroma of the hand: the role of biopsy in the course of diagnosis and treatment
Abstract Background: Enchondroma, is the most frequent bone tumor of the hand , but chondrosarcoma is rare at this location .There is a high possibility of correct diagnosis of enchondroma and differentiating from its malignant counterpart by precise clinical and radiologic assessment without biopsy, a subject of debate in the literature . At the present study we substantially investigate this...
متن کاملMast cells density in fibrotic capsule of enchondroma and well-differentiated chondrosarcoma: a method for histopathologic differentiation
Background: An enchondroma is a benign and a well-differentiated chondrosarcoma is an invasive chondroid tumor with high recurrence potential. In spite of biologic differences, these two tumors have very similar histopathologic appearance. It has been shown that the biologic nature of the connective tissue around benign and malignant tumors varies in the number of mast cells. The aim of this s...
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